Michelle Paucar

Affiliations

One Health Research Group, Faculty of Health Sciences, Universidad de Las Américas, Quito, Ecuador.

ORCID: 0000-0002-6660-6959

Publications (33)

A Novel Duplication in ATXN2 as Modifier for Spinocerebellar Ataxia 3 (SCA3) and C9ORF72-ALS.

Movement disorders : official journal of the Movement Disorder Society

Avec: Jose Miguel Laffita-Mesa , Inger Nennesmo , Martin Paucar , Per Svenningsson

Proenkephalin Decreases in Cerebrospinal Fluid with Symptom Progression of Huntington's Disease.

Movement disorders : official journal of the Movement Disorder Society

Avec: Valter Niemela , Anne-Marie Landtblom , Dag Nyholm , Maria Kneider , Radu Constantinescu , Martin Paucar , Per Svenningsson , Sandy Abujrais , Joachim Burman , Ganna Shevchenko , Jonas Bergquist , Jimmy Sundblom

Ataxin-2 gene: a powerful modulator of neurological disorders.

Current opinion in neurology

Avec: Jose Miguel Laffita-Mesa , Martin Paucar , Per Svenningsson

Variations in the financial impact of the COVID-19 pandemic across 5 continents: A cross-sectional, individual level analysis.

EClinicalMedicine

Avec: Aditya K Khetan , Salim Yusuf , Patricio Lopez-Jaramillo , Andrzej Szuba , Andres Orlandini , Nafiza Mat-Nasir , Aytekin Oguz , Rajeev Gupta , Álvaro Avezum , Ismail Rosnah , Paul Poirier , Koon K Teo , Andreas Wielgosz , Scott A Lear , Lia M Palileo-Villanueva , Pamela Serón , Jephat Chifamba , Sumathy Rangarajan , Maha Mushtaha , Deepa Mohan , Karen Yeates , Martin McKee , Prem K Mony , Marjan Walli-Attaei , Hamda Khansaheb , Annika Rosengren , Khalid F Alhabib , Iolanthé M Kruger , María-José Paucar , Erkin Mirrakhimov , Batyrbek Assembekov , Darryl P Leong

The clinical spectrum of ataxia telangiectasia in a cohort in Sweden.

Heliyon

Avec: Hannes Lindahl , Eva Svensson , Annika Danielsson , Andreas Puschmann , Per Svenningson , Bianca Tesi , Martin Paucar

Neuropathy with Cerebral Features Induced by Nitrous Oxide Abuse-A Case Report.

Toxics

Avec: Erik Lindeman , Sara Melin , Martin Paucar , Richard Ågren

Ataxia Syndrome With Hearing Loss and Nephronophthisis Associated With a Novel Homozygous Variant in

Neurology. Genetics

Avec: Ilan Ben-Shabat , Malin Kvarnung , Wolfgang Sperker , Helene Bruhn , Anna Wredenberg , Rolf Wibom , Inger Nennesmo , Martin Engvall , Martin Paucar

Altered CSF levels of monoamines in hereditary spastic paraparesis 10: A case series.

Neurology. Genetics

Avec: Mattias Andréasson , Kristina Lagerstedt-Robinson , Kristin Samuelsson , Göran Solders , Kaj Blennow , Martin Paucar , Per Svenningsson

[Ataxia - a group of heterogeneous diseases].

Lakartidningen

Avec: Martin Paucar , Niklas Dahl , Martin Engvall , Per Svenningsson , Göran Solders

Genome sequencing with comprehensive variant calling identifies structural variants and repeat expansions in a large fraction of individuals with ataxia and/or neuromuscular disorders.

Frontiers in neurology

Avec: Marlene Ek , Daniel Nilsson , Martin Engvall , Helena Malmgren , Håkan Thonberg , Maria Pettersson , Britt-Marie Anderlid , Anna Hammarsjö , Hafdis T Helgadottir , Snjolaug Arnardottir , Karin Naess , Inger Nennesmo , Martin Paucar , Helgi Thor Hjartarson , Rayomand Press , Göran Solders , Thomas Sejersen , Anna Lindstrand , Malin Kvarnung

Phenotypic variability in a large kindred with spastic paraplegia associated with a novel

eNeurologicalSci

Avec: Helgi Thor Hjartarson , Humberto Skott , Tobias Granberg , Martin Paucar

Cerebrospinal fluid glial fibrillary acidic protein, in contrast to amyloid beta protein, is associated with disease symptoms in Huntington's disease.

Journal of the neurological sciences

Avec: Sara Korpela , Jimmy Sundblom , Henrik Zetterberg , Radu Constantinescu , Per Svenningsson , Martin Paucar , Valter Niemelä

[Orthostatic tremor - a disregarded diagnosis].

Lakartidningen

Avec: Karolina Af Edholm Arvidsson , Martin Paucar , Per Svenningsson

Broader phenotypic traits and widespread brain hypometabolism in spinocerebellar ataxia 27.

Journal of internal medicine

Avec: M Paucar , J Lundin , T Alshammari , Å Bergendal , M Lindefeldt , M Alshammari , G Solders , J Di Re , I Savitcheva , T Granberg , F Laezza , E Iwarsson , P Svenningsson

Heterozygous variants in

Neurology. Genetics

Avec: Sebastian Thams , Mominul Islam , Marie Lindefeldt , Ann Nordgren , Tobias Granberg , Bianca Tesi , Gisela Barbany , Daniel Nilsson , Martin Paucar

Natural History, Phenotypic Spectrum, and Discriminative Features of Multisystemic RFC1 Disease.

Neurology

Avec: Andreas Traschütz , Andrea Cortese , Selina Reich , Natalia Dominik , Jennifer Faber , Heike Jacobi , Annette M Hartmann , Dan Rujescu , Solveig Montaut , Andoni Echaniz-Laguna , Sevda Erer , Valerie Cornelia Schütz , Alexander A Tarnutzer , Marc Sturm , Tobias B Haack , Nadège Vaucamps-Diedhiou , Helene Puccio , Ludger Schöls , Thomas Klockgether , Bart P van de Warrenburg , Martin Paucar , Dagmar Timmann , Ralf-Dieter Hilgers , Jose Gazulla , Michael Strupp , German Moris , Alessandro Filla , Henry Houlden , Mathieu Anheim , Jon Infante , A Nazli Basak , Matthis Synofzik , Auteur inconnu

On Spinocerebellar Ataxia 21 as a Mimicker of Cerebral Palsy.

Neurology. Genetics

Avec: Johanna van der Put , Dalia Daugeliene , Åsa Bergendal , Malin Kvarnung , Per Svenningsson , Martin Paucar

Genome sequencing is a sensitive first-line test to diagnose individuals with intellectual disability.

Genetics in medicine : official journal of the American College of Medical Genetics

Avec: Anna Lindstrand , Marlene Ek , Malin Kvarnung , Britt-Marie Anderlid , Erik Björck , Jonas Carlsten , Jesper Eisfeldt , Giedre Grigelioniene , Peter Gustavsson , Anna Hammarsjö , Hafdís T Helgadóttir , Maritta Hellström-Pigg , Ekaterina Kuchinskaya , Kristina Lagerstedt-Robinson , Lars-Åke Levin , Agne Lieden , Hillevi Lindelöf , Helena Malmgren , Daniel Nilsson , Eva Svensson , Martin Paucar , Ellika Sahlin , Bianca Tesi , Emma Tham , Johanna Winberg , Max Winerdal , Josephine Wincent , Maria Johansson Soller , Maria Pettersson , Ann Nordgren

An E280K Missense Variant in

International journal of molecular sciences

Avec: Richard Ågren , Niels Geerdink , Han G Brunner , Martin Paucar , Erik-Jan Kamsteeg , Kristoffer Sahlholm

Spinocerebellar ataxia type 4 is caused by a GGC expansion in the ZFHX3 gene and is associated with prominent dysautonomia and motor neuron signs.

Journal of internal medicine

Avec: Martin Paucar , Daniel Nilsson , Martin Engvall , José Laffita-Mesa , Cilla Söderhäll , Mikael Skorpil , Christer Halldin , Patrik Fazio , Kristina Lagerstedt-Robinson , Göran Solders , Maria Angeria , Andrea Varrone , Mårten Risling , Hong Jiao , Inger Nennesmo , Anna Wedell , Per Svenningsson

The protean presentations of XK disease (McLeod syndrome): a case series with new observations and updates on previously reported families.

Frontiers in neuroscience

Avec: Ruth H Walker , Mariana Barreto , James R Bateman , M Leonor Bustamante , Graham Chiu , Scott Feitell , Beat M Frey , Patricio Guerra , Sofia Guerrero , Hans H Jung , Fernando Maldonado , Eduardo Meyer , Marcelo Miranda , Emelie McFarland , Patricia Oates , Gorka Ochoa , Karin Olsson , Martin Paucar , Jonatan Alvarez Proschle , Esther M Sammler , Monica Troncoso , Rachel Wu-Wallace , Leo Young , Sunitha Vege , Connie M Westhoff , Adrian Danek

Assessing the burden and spatial distribution of Taenia solium human neurocysticercosis in Ecuador (2013-2017).

PLoS neglected tropical diseases

Avec: Marco Coral-Almeida , Aquiles R Henriquez-Trujillo , Sofia Asanza , Celia Erazo , Michelle Paucar , Manuel Calvopiña

The cerebellar phenotype of Charcot-Marie-Tooth neuropathy type 4C.

Cerebellum & ataxias

Avec: Humberto Skott , Cristina Muntean-Firanescu , Kristin Samuelsson , Luca Verrecchia , Per Svenningsson , Helena Malmgren , Carmen Cananau , Alberto J Espay , Rayomand Press , Göran Solders , Martin Paucar

Progressive Ataxia with Elevated Alpha-Fetoprotein: Diagnostic Issues and Review of the Literature.

Tremor and other hyperkinetic movements (New York, N.Y.)

Avec: Martin Paucar , Alexander M R Taylor , Marios Hadjivassiliou , Brent L Fogel , Per Svenningsson

Increasing involvement of CAPN1 variants in spastic ataxias and phenotype-genotype correlations.

Neurogenetics

Avec: Jean-Loup Méreaux , Cristina Firanescu , Giulia Coarelli , Malin Kvarnung , Rita Rodrigues , Elena Pegoraro , Meriem Tazir , Frédéric Taithe , Rémi Valter , Vincent Huin , Kristina Lidström , Guillaume Banneau , Sara Morais , Livia Parodi , Marie Coutelier , Mélanie Papin , Per Svenningsson , Jean-Philippe Azulay , Isabel Alonso , Daniel Nilsson , Alexis Brice , Eric Le Guern , Rayomand Press , Giovanni Vazza , José Leal Loureiro , Cyril Goizet , Alexandra Durr , Martin Paucar , Giovanni Stevanin

Phenotypic variability in chorea-acanthocytosis associated with novel

Neurology. Genetics

Avec: Valter Niemelä , Ammar Salih , Daniela Solea , Björn Lindvall , Jan Weinberg , Gabriel Miltenberger , Tobias Granberg , Aikaterini Tzovla , Love Nordin , Torsten Danfors , Irina Savitcheva , Niklas Dahl , Martin Paucar

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

BMC medical genetics

Avec: Andrea Bieder , Elisabet Einarsdottir , Hans Matsson , Harriet E Nilsson , Jesper Eisfeldt , Anca Dragomir , Martin Paucar , Tobias Granberg , Tie-Qiang Li , Anna Lindstrand , Juha Kere , Isabel Tapia-Páez

[Recent advances in Huntington's disease].

Lakartidningen

Avec: Valter Niemelä , Åsa Petersén , Ghada Loutfi , Per Svenningsson , Martin Paucar

V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations.

Neurology. Genetics

Avec: Martin Paucar , Richard Ågren , Tianyi Li , Simon Lissmats , Åsa Bergendal , Jan Weinberg , Daniel Nilsson , Irina Savichetva , Kristoffer Sahlholm , Johanna Nilsson , Per Svenningsson

Genetic screening for Huntington disease phenocopies in Sweden: A tertiary center case series focused on short tandem repeat (STR) disorders.

Journal of the neurological sciences

Avec: Martin Paucar , José Laffita-Mesa , Valter Niemelä , Helena Malmgren , Inger Nennesmo , Kristina Lagerstedt-Robinson , Magnus Nordenskjöld , Per Svenningsson

Long-term administration of intravenous Trappsol® Cyclo™ (HP-β-CD) results in clinical benefits and stabilization or slowing of disease progression in patients with Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial.

Molecular genetics and metabolism reports

Avec: Reena Sharma , Caroline Hastings , Orna Staretz-Chacham , Julian Raiman , Martin Paucar , Ronen Spiegel , Bryan Murray , Bryan Hurst , Benny Liu , Lise Kjems , Sharon Hrynkow

Novel findings in a Swedish primary familial brain calcification cohort.

Journal of the neurological sciences

Avec: Stefan Sennfält , Peter Gustavsson , Helena Malmgren , Eric Gilland , Håkan Almqvist , Mikael Oscarson , Martin Engvall , Ingemar Björkhem , Daniel Nilsson , Kristina Lagerstedt-Robinson , Per Svenningsson , Martin Paucar

Case report: Neuroacanthocytosis associated with novel variants in the

Frontiers in neuroscience

Avec: Martin Paucar , Josephine Wincent , Charlotta Rubin , Kevin Peikert , Josefin Kyhle , Stellan Hertegård , Riita Möller , Soheir Beshara , Per Svenningsson

Réseau de co-auteurs

Martin Paucar 30 collaborations

Per Svenningsson 17 collaborations

Daniel Nilsson 7 collaborations

Inger Nennesmo 5 collaborations

Malin Kvarnung 5 collaborations

Martin Engvall 5 collaborations

Kristina Lagerstedt-Robinson 5 collaborations

Göran Solders 5 collaborations

Helena Malmgren 5 collaborations

Tobias Granberg 4 collaborations

Valter Niemelä 4 collaborations

Bianca Tesi 3 collaborations

Richard Ågren 3 collaborations

Rayomand Press 3 collaborations

Anna Lindstrand 3 collaborations

Jose Miguel Laffita-Mesa 2 collaborations

Radu Constantinescu 2 collaborations

Jimmy Sundblom 2 collaborations

Eva Svensson 2 collaborations

Kristin Samuelsson 2 collaborations

Niklas Dahl 2 collaborations

Marlene Ek 2 collaborations

Maria Pettersson 2 collaborations

Britt-Marie Anderlid 2 collaborations

Anna Hammarsjö 2 collaborations

Helgi Thor Hjartarson 2 collaborations

Humberto Skott 2 collaborations

Ann Nordgren 2 collaborations

Åsa Bergendal 2 collaborations

Jesper Eisfeldt 2 collaborations

Peter Gustavsson 2 collaborations

Josephine Wincent 2 collaborations

Kristoffer Sahlholm 2 collaborations

José Laffita-Mesa 2 collaborations

Jan Weinberg 2 collaborations

Valter Niemela 1 collaboration

Anne-Marie Landtblom 1 collaboration

Dag Nyholm 1 collaboration

Maria Kneider 1 collaboration

Sandy Abujrais 1 collaboration

Joachim Burman 1 collaboration

Ganna Shevchenko 1 collaboration

Jonas Bergquist 1 collaboration

Aditya K Khetan 1 collaboration

Salim Yusuf 1 collaboration

Patricio Lopez-Jaramillo 1 collaboration

Andrzej Szuba 1 collaboration

Andres Orlandini 1 collaboration

Nafiza Mat-Nasir 1 collaboration

Aytekin Oguz 1 collaboration

Rajeev Gupta 1 collaboration

Álvaro Avezum 1 collaboration

Ismail Rosnah 1 collaboration

Paul Poirier 1 collaboration

Koon K Teo 1 collaboration

Andreas Wielgosz 1 collaboration

Scott A Lear 1 collaboration

Lia M Palileo-Villanueva 1 collaboration

Pamela Serón 1 collaboration

Jephat Chifamba 1 collaboration

Sumathy Rangarajan 1 collaboration

Maha Mushtaha 1 collaboration

Deepa Mohan 1 collaboration

Karen Yeates 1 collaboration

Martin McKee 1 collaboration

Prem K Mony 1 collaboration

Marjan Walli-Attaei 1 collaboration

Hamda Khansaheb 1 collaboration

Annika Rosengren 1 collaboration

Khalid F Alhabib 1 collaboration

Iolanthé M Kruger 1 collaboration

María-José Paucar 1 collaboration

Erkin Mirrakhimov 1 collaboration

Batyrbek Assembekov 1 collaboration

Darryl P Leong 1 collaboration

Hannes Lindahl 1 collaboration

Annika Danielsson 1 collaboration

Andreas Puschmann 1 collaboration

Per Svenningson 1 collaboration

Erik Lindeman 1 collaboration

Sara Melin 1 collaboration

Ilan Ben-Shabat 1 collaboration

Wolfgang Sperker 1 collaboration

Helene Bruhn 1 collaboration

Anna Wredenberg 1 collaboration

Rolf Wibom 1 collaboration

Mattias Andréasson 1 collaboration

Kaj Blennow 1 collaboration

Håkan Thonberg 1 collaboration

Hafdis T Helgadottir 1 collaboration

Snjolaug Arnardottir 1 collaboration

Karin Naess 1 collaboration

Thomas Sejersen 1 collaboration

Sara Korpela 1 collaboration

Henrik Zetterberg 1 collaboration

Karolina Af Edholm Arvidsson 1 collaboration

M Paucar 1 collaboration

J Lundin 1 collaboration

T Alshammari 1 collaboration

Å Bergendal 1 collaboration

M Lindefeldt 1 collaboration

M Alshammari 1 collaboration

G Solders 1 collaboration

J Di Re 1 collaboration

I Savitcheva 1 collaboration

T Granberg 1 collaboration

F Laezza 1 collaboration

E Iwarsson 1 collaboration

P Svenningsson 1 collaboration

Sebastian Thams 1 collaboration

Mominul Islam 1 collaboration

Marie Lindefeldt 1 collaboration

Gisela Barbany 1 collaboration

Andreas Traschütz 1 collaboration

Andrea Cortese 1 collaboration

Selina Reich 1 collaboration

Natalia Dominik 1 collaboration

Jennifer Faber 1 collaboration

Heike Jacobi 1 collaboration

Annette M Hartmann 1 collaboration

Dan Rujescu 1 collaboration

Solveig Montaut 1 collaboration

Andoni Echaniz-Laguna 1 collaboration

Sevda Erer 1 collaboration

Valerie Cornelia Schütz 1 collaboration

Alexander A Tarnutzer 1 collaboration

Marc Sturm 1 collaboration

Tobias B Haack 1 collaboration

Nadège Vaucamps-Diedhiou 1 collaboration

Helene Puccio 1 collaboration

Ludger Schöls 1 collaboration

Thomas Klockgether 1 collaboration

Bart P van de Warrenburg 1 collaboration

Dagmar Timmann 1 collaboration

Ralf-Dieter Hilgers 1 collaboration

Jose Gazulla 1 collaboration

Michael Strupp 1 collaboration

German Moris 1 collaboration

Alessandro Filla 1 collaboration

Henry Houlden 1 collaboration

Mathieu Anheim 1 collaboration

Jon Infante 1 collaboration

A Nazli Basak 1 collaboration

Matthis Synofzik 1 collaboration

None None 1 collaboration

Johanna van der Put 1 collaboration

Dalia Daugeliene 1 collaboration

Erik Björck 1 collaboration

Jonas Carlsten 1 collaboration

Giedre Grigelioniene 1 collaboration

Hafdís T Helgadóttir 1 collaboration

Maritta Hellström-Pigg 1 collaboration

Ekaterina Kuchinskaya 1 collaboration

Lars-Åke Levin 1 collaboration

Agne Lieden 1 collaboration

Hillevi Lindelöf 1 collaboration

Ellika Sahlin 1 collaboration

Emma Tham 1 collaboration

Johanna Winberg 1 collaboration

Max Winerdal 1 collaboration

Maria Johansson Soller 1 collaboration

Niels Geerdink 1 collaboration

Han G Brunner 1 collaboration

Erik-Jan Kamsteeg 1 collaboration

Cilla Söderhäll 1 collaboration

Mikael Skorpil 1 collaboration

Christer Halldin 1 collaboration

Patrik Fazio 1 collaboration

Maria Angeria 1 collaboration

Andrea Varrone 1 collaboration

Mårten Risling 1 collaboration

Hong Jiao 1 collaboration

Anna Wedell 1 collaboration

Ruth H Walker 1 collaboration

Mariana Barreto 1 collaboration

James R Bateman 1 collaboration

M Leonor Bustamante 1 collaboration

Graham Chiu 1 collaboration

Scott Feitell 1 collaboration

Beat M Frey 1 collaboration

Patricio Guerra 1 collaboration

Sofia Guerrero 1 collaboration

Hans H Jung 1 collaboration

Fernando Maldonado 1 collaboration

Eduardo Meyer 1 collaboration

Marcelo Miranda 1 collaboration

Emelie McFarland 1 collaboration

Patricia Oates 1 collaboration

Gorka Ochoa 1 collaboration

Karin Olsson 1 collaboration

Jonatan Alvarez Proschle 1 collaboration

Esther M Sammler 1 collaboration

Monica Troncoso 1 collaboration

Rachel Wu-Wallace 1 collaboration

Leo Young 1 collaboration

Sunitha Vege 1 collaboration

Connie M Westhoff 1 collaboration

Adrian Danek 1 collaboration

Marco Coral-Almeida 1 collaboration

Aquiles R Henriquez-Trujillo 1 collaboration

Sofia Asanza 1 collaboration

Celia Erazo 1 collaboration

Manuel Calvopiña 1 collaboration

Cristina Muntean-Firanescu 1 collaboration

Luca Verrecchia 1 collaboration

Carmen Cananau 1 collaboration

Alberto J Espay 1 collaboration

Alexander M R Taylor 1 collaboration

Marios Hadjivassiliou 1 collaboration

Brent L Fogel 1 collaboration

Jean-Loup Méreaux 1 collaboration

Cristina Firanescu 1 collaboration

Giulia Coarelli 1 collaboration

Rita Rodrigues 1 collaboration

Elena Pegoraro 1 collaboration

Meriem Tazir 1 collaboration

Frédéric Taithe 1 collaboration

Rémi Valter 1 collaboration

Vincent Huin 1 collaboration

Kristina Lidström 1 collaboration

Guillaume Banneau 1 collaboration

Sara Morais 1 collaboration

Livia Parodi 1 collaboration

Marie Coutelier 1 collaboration

Mélanie Papin 1 collaboration

Jean-Philippe Azulay 1 collaboration

Isabel Alonso 1 collaboration

Alexis Brice 1 collaboration

Eric Le Guern 1 collaboration

Giovanni Vazza 1 collaboration

José Leal Loureiro 1 collaboration

Cyril Goizet 1 collaboration

Alexandra Durr 1 collaboration

Giovanni Stevanin 1 collaboration

Ammar Salih 1 collaboration

Daniela Solea 1 collaboration

Björn Lindvall 1 collaboration

Gabriel Miltenberger 1 collaboration

Aikaterini Tzovla 1 collaboration

Love Nordin 1 collaboration

Torsten Danfors 1 collaboration

Irina Savitcheva 1 collaboration

Andrea Bieder 1 collaboration

Elisabet Einarsdottir 1 collaboration

Hans Matsson 1 collaboration

Harriet E Nilsson 1 collaboration

Anca Dragomir 1 collaboration

Tie-Qiang Li 1 collaboration

Juha Kere 1 collaboration

Isabel Tapia-Páez 1 collaboration

Åsa Petersén 1 collaboration

Ghada Loutfi 1 collaboration

Tianyi Li 1 collaboration

Simon Lissmats 1 collaboration

Irina Savichetva 1 collaboration

Johanna Nilsson 1 collaboration

Magnus Nordenskjöld 1 collaboration

Reena Sharma 1 collaboration

Caroline Hastings 1 collaboration

Orna Staretz-Chacham 1 collaboration

Julian Raiman 1 collaboration

Ronen Spiegel 1 collaboration

Bryan Murray 1 collaboration

Bryan Hurst 1 collaboration

Benny Liu 1 collaboration

Lise Kjems 1 collaboration

Sharon Hrynkow 1 collaboration

Stefan Sennfält 1 collaboration

Eric Gilland 1 collaboration

Håkan Almqvist 1 collaboration

Mikael Oscarson 1 collaboration

Ingemar Björkhem 1 collaboration

Charlotta Rubin 1 collaboration

Kevin Peikert 1 collaboration

Josefin Kyhle 1 collaboration

Stellan Hertegård 1 collaboration

Riita Möller 1 collaboration

Soheir Beshara 1 collaboration